Furthermore, the size of this effect correlated with volunteers' ratings of complex, dreamlike visions. We saw that many more areas of the brain than normal were contributing to visual processing under LSD - even though the volunteers' eyes were closed. However, when the volunteers took LSD, many additional brain areas - not just the visual cortex - contributed to visual processing.ĭr Robin Carhart-Harris, from the Department of Medicine at Imperial, who led the research, explained: "We observed brain changes under LSD that suggested our volunteers were 'seeing with their eyes shut' - albeit they were seeing things from their imagination rather than from the outside world. Under normal conditions, information from our eyes is processed in a part of the brain at the back of the head called the visual cortex. Scientists have waited 50 years for this moment - the revealing of how LSD alters our brain biologyĪ major finding of the research is the discovery of what happens in the brain when people experience complex dreamlike hallucinations under LSD.
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